Thyroid nodule is a common clinical problem, and nodular thyroid disease is prevailing in our population. Ultrasound is frequently employed to screen for thyroid lesions and to complement other relevant investigations. Fine needle aspiration cytology is frequently performed under ultrasound guidance. Surgical treatment should be considered for nodules suspicious of malignancy, symptomatic nodules, the presence of objective pressure symptoms or progressive increased in size with monitoring. Thyroid function blood tests including free thyroxine and thyroid-stimulating hormone levels should be performed to exclude concomitant hyper or hypothyroidism.